Bryan Johnson, a billionaire tech entrepreneur turned biohacker, has been in the news for trying unusual ways to reverse aging. He spends a huge $2 million every year on this goal. Johnson wants to turn back time on his body and live much longer—maybe even forever.
He’s become famous for doing strange medical experiments, like getting blood transfusions from his younger son and doing full plasma exchanges. His efforts to stay young have made a lot of people pay attention to him and his family.
But recently, Johnson admitted that chasing youth so hard may have done more harm than good, though he didn’t explain exactly how.
Bryan Johnson’s Rapamycin Test: Trying a Drug to Live Longer
One key part of Bryan Johnson’s plan to slow down aging was using a drug called rapamycin. This drug was first made to help people who got organ transplants by stopping their immune system from attacking the new organ. But recently, some people who study aging think it might help people live longer.
Johnson started using rapamycin after seeing a 2009 study where it helped mice live up to 14% longer. He also looked at a 2023 study on humans that showed hopeful results. For five years, he took the drug and kept changing the dose, trying to find the right balance between possible benefits and risks.
Bryan Johnson’s Rapamycin Side Effects and the Study That Made Him Rethink Everything
Instead of feeling younger like he had hoped, Bryan Johnson started to have some worrying side effects from rapamycin. The drug caused painful mouth sores, slow healing of cuts, changes in cholesterol levels, and even high blood sugar. The most concerning problem for him was a rise in his resting heart rate, which he believes is a key sign of how well his body is recovering and sleeping.
These issues made Johnson stop and rethink his plan.
Adding to his concern was a new study from Yale University. The study went against earlier research and suggested that rapamycin might not slow aging at all, in fact, it could make it happen faster. Scientists found that the drug negatively affected 16 important markers in the body that are linked to aging. For Johnson, this was a wake-up call. It made him realize that his efforts to stay young might have actually done the opposite.
Bryan Johnson Admits Setback but Stays Committed to His Biohacking Journey
In a recent video, Bryan Johnson openly talked about the surprising turn in his experiment. He laughed at himself and said, “To those of you laughing at home, I’m laughing with you,” showing he wasn’t embarrassed by the failure. He shared that he had stopped taking rapamycin, but made it clear that this wasn’t the end of his journey, just a fresh start.
Johnson believes in trying new things and being honest about what works and what doesn’t. He said it’s important to share both the wins and the mistakes. For him, every step, good or bad, is a chance to learn and grow.
Bryan Johnson is using his own money to test how far we can go to live longer, but it comes with big risks. Some people think he’s a genius, while others doubt his methods. No matter what you believe, one thing is clear: even with careful planning, trying to fight aging can sometimes make it worse.
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