Question
Download Solution PDFIdentify major product 'P' formed in the following reaction.
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AIIMS BSc NURSING 2024 Memory-Based Paper
Answer (Detailed Solution Below)
Option 4 :
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AIIMS BSc NURSING 2024 Memory-Based Paper
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Detailed Solution
Download Solution PDFCONCEPT:
Friedel-Crafts Acylation
- Friedel-Crafts acylation is a reaction where an acyl group (RCO-) is introduced to an aromatic ring (such as benzene) using an acyl chloride (RCOCl) and a Lewis acid (usually AlCl3).
- This reaction is an electrophilic aromatic substitution in which the acyl group replaces a hydrogen atom on the aromatic ring.
- The AlCl3 acts as a catalyst and helps in the generation of the acylium ion (RCO+), which is a highly electrophilic species that attacks the aromatic ring.
EXPLANATION:
- In the given reaction:
C6H6 + RCOCl → C6H5CO-R
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- The acyl chloride (RCOCl) reacts with AlCl3 to form the acylium ion (RCO+), which then attacks the benzene ring.
- The mechanism of the reaction involves:
- Generation of the acylium ion (RCO+) by the interaction of acyl chloride with AlCl3.
- Attack of the acylium ion on the benzene ring to form the intermediate complex.
- Loss of a proton from the intermediate complex results in the final product, an aryl ketone (C6H5CO-R).
Therefore, the major product 'P' formed in the reaction is an aryl ketone (C6H5CO-R).
Last updated on Jun 17, 2025
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