On 4 June 2021, India’s first CAR-T cell therapy, which was done at Mumbai’s Tata Memorial Centre, was for which of the following ailments?

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RRB Group D 20 Sept 2022 Shift 1 Official Paper
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  1. Bone Transplant
  2. Blood cancer
  3. Lung Transplant
  4. AIDS

Answer (Detailed Solution Below)

Option 2 : Blood cancer
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Detailed Solution

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The correct answer is Blood cancer.

Key Points

  • The first CAR-T cell treatment (a sort of gene therapy) was performed at the Bone Marrow Transplant unit at ACTREC, Tata Memorial Center in Mumbai on June 4, 2021, making it a momentous day for TMH, the IIT Bombay team, and cancer care in India.
  • The Bioscience and Bioengineering (BSBE) department of IIT Bombay created and produced CAR-T cells.
  • The BIRAC-PACE programme partially funds this work.
  • DBT/BIRAC further sponsors the TMC-IIT Bombay team through the National Biopharma Mission to prolong this initiative for conducting Phase I/II trials of their CAR-T product.

Additional Information

  • Bone Transplant 
    • Changing the bone marrow of a patient is known as a stem cell transplant. If the bone marrow stops functioning and does not create enough healthy blood cells, patients may require a bone marrow transplant.
    • Cells from a donor or one's own body can be used in a bone marrow transplant (autologous transplant).
  • Lung Transplant
    • One or both of the patient's lungs may be replaced via a surgical surgery known as a lung transplant, also known as a pulmonary transplant. Either a living or deceased donor can provide donors. A living donor is limited to giving one lung lobe.
    • A recipient may only need to receive one lung if they have certain pulmonary conditions.
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