Question
Download Solution PDFThe major product formed in the following reaction sequence is
Answer (Detailed Solution Below)
Detailed Solution
Download Solution PDFConcept:
Sharpless epoxidation, named after Nobel laureate K. Barry Sharpless, is a widely used asymmetric epoxidation reaction that allows for the selective synthesis of chiral epoxides from olefins (alkenes). Epoxides are three-membered cyclic ethers characterized by a ring containing an oxygen atom and two adjacent carbon atoms.
Explanation:
- In Sharpless Epoxidation, (-) DET initiates the attack of nucleophile from above the plane.
- The oxirane then reacts with Red Al to form diol.
Conclusion:
Hence, the major product form in the reaction is (S)-phenylpropane-1,3-diol.
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