The major product formed in the following reaction sequence is

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CSIR-UGC (NET) Chemical Science: Held on (18 Sept 2022)
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Answer (Detailed Solution Below)

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Concept:

Sharpless epoxidation, named after Nobel laureate K. Barry Sharpless, is a widely used asymmetric epoxidation reaction that allows for the selective synthesis of chiral epoxides from olefins (alkenes). Epoxides are three-membered cyclic ethers characterized by a ring containing an oxygen atom and two adjacent carbon atoms.

Explanation:

  • In Sharpless Epoxidation, (-) DET initiates the attack of nucleophile from above the plane.

  • The oxirane then reacts with Red Al to form diol.

Conclusion:

Hence, the major product form in the reaction is (S)-phenylpropane-1,3-diol.

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