Which is a nutritional disorder caused by vitamin B3 deficiency, leading to clinical manifestations from the skin gastrointestinal tract and nervous system?

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SSC CHSL Exam 2023 Tier-I Official Paper (Held On: 02 Aug, 2023 Shift 2)
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  1. Anaemia
  2. Pellagra
  3. Beri Beri
  4. Scurvy

Answer (Detailed Solution Below)

Option 2 : Pellagra
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SSC CHSL Exam 2023 Tier-I Official Paper (Held On: 02 Aug 2023 Shift 1)
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Detailed Solution

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The correct answer is Pellagra.

Key Points

  • Pellagra is a nutritional disorder caused by vitamin B3 (niacin) deficiency.
  • Clinical manifestations of pellagra include skin rashes, diarrhea, dementia, and eventually death if left untreated.
  • Vitamin B3 is important for energy production, metabolism, and DNA repair.
  • Pellagra was once a common disease in the United States, particularly in the southern states, but it became rare after the fortification of grain products with niacin.

Additional Information

  • Anaemia:
    • Anemia is a blood condition where the blood's capacity to carry oxygen is diminished because there are fewer red blood cells in the blood than usual.
    • It can be caused by various factors such as iron deficiency, vitamin B12 deficiency, or chronic disease.
  • Beri Beri:
    • It is a disease caused by thiamine (vitamin B1) deficiency.
    • It can lead to symptoms such as fatigue, muscle weakness, and nerve damage.
  • Scurvy:
    • It is a disease caused by vitamin C deficiency.
    • It can lead to symptoms such as bleeding gums, skin rash, and joint pain.
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